In her own words to The Sunday Mirror she stated: "I'm not like those glamour girls who say: 'I'm really dirty, I'm really bad', then just pose around. I really am dirty and bad - I love sex."
She took up presenting on pornographic channel Television X, released a fitness video, authored an erotic novel published by Black Lace, and made personal appearances in nightclubs all over the UK and Ireland. After a photo shoot opportunity offered by FHM of a two page spread, she eventually was featured in a three page spread and made the cover. In the following year, she made 38 front page appearances in 2004 and 2005 for many UK men's magazines, such as FHM , Nuts, Zoo Weekly, Loaded, GQ and Maxim magazines, others such as The Sunday Times Style and topless on page 3 of several tabloid newspapers including The Sun, The News Of The World, The Daily Mirror, The People and Daily Star - each photoshot made her a minimum of £20,000 per session. Titmuss was voted by readers as #7 in FHM 100 Sexiest Women in the World 2005, and wrote a regular sex advice column for the magazine. In December 2004, Titmuss appeared on the front cover of FHM magazine with Victoria Silvstedt. At the height of her fame in 2004/5, she could command up to £30,000 a day for appearing on the front page of Nuts or Zoo.
She appeared on ITV1's Celebrity Love Island. Her other television work includes training as a chef on the 2004 series of Hell's Kitchen, and in 2005, she appeared on Channel 4's The Friday Night Project as a regular guest feature, and in "Abi Titmuss: A Modern Day Morality Tale", a fly-on-the-wall documentary for Channel 4. She has also starred on Channel 4's Come Dine With Me.
In 2005, Titmuss appeared in a high fashion shoot in Pop magazine, which commented on her status as the Face of 21st century celebrity.
After taking a break from modelling work, Titmuss relaunched her glamour career as a brunette with an appearance on the cover of Zoo magazine and the sale of the official Abi Titmuss Calendar 2007.
On 25 April 2007, it was announced that Titmuss had made an appearance for a third year running in FHM's annual 100 Sexiest Women in the World readers' poll, at #80 (#7 in 2005, #95 in 2004), however Titmuss has recently announced her intention to take a break from the world of glamour modelling.
Titmuss returned to glamour modelling with a new Nuts shoot in April 2009. Titmuss attracted controversy after appearing in Loaded magazine rubbing her own faeces on a blow-up doll of former partner John Leslie. Titmuss later said she regretted the shoot